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positive regulation), and somatostatin (negative regulation) (Fig

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GLP-1 medications can be a powerful tool for people to improve their health, but theyre not for everyone

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Tirzepatide has been approved for T2D management - the mean HbA1c reduction in SURPASS programme ranged between 1.9 and 2.6% across the trials and 4069% of participants achieved 10% WL with the higher doses (10 and 15 mg), despite that there was no additional support for lifestyle intervention [16, 43]