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It regulates inflammatory signaling, immune cell function, and mitochondrial energy productionfunctions that vary significantly based on individual synthesis capacity and genetic factors affecting glutathione biosynthesis enzymes
The addition of exogenous ROS results in resensitization of cells with high VRK2 expression to GSH inhibition, which is consistent with the fact that PC cells with low expression of VRK2 are susceptible to GSH inhibition attributes to its high basal ROS level, suggesting that cells in a state of oxidative stress have enhanced dependence on the GSH system
Cicinelli, E
It may help protect skin from free radical damage and support collagen production
doi:10.1007/978-94-007-7500-8_8
J NSC 26 : 1204312054
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