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Xie H et al

The second question relates to what was described as perceived excessive weight loss in the extension period of the SURMOUNT-1 study, where dose modifications of the blinded study drug were allowed to support patient management and retention during the additional two-year treatment phase

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Administration of lipoic acid (200 to 1,800 mg/day for 2 weeks to 1 year), alone or together with other nutrients, was found to lower fasting blood glucose and insulin concentrations, insulin resistance, and blood HbA1c concentration a marker of glycemic control over the past few months (60)

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Glutamine is generally considered the better choice for direct gut support because it is the primary fuel source for the cells that make up your intestinal lining