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This rare tumor was first described by Millar in 1932, as a "malignant melanotic tumor of the ganglion cells arising from the thoracic sympathetic ganglion." 13 It was later identified as a subtype of schwannoma in 1961 by Hodson 34 before subsequently being termed "melanocytic schwannoma" in 1975 by Fu et al

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When the research question specifically isolates these two mechanisms, adding GHK-Cu introduces confounding from its gene-expression and anti-inflammatory effects

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For psoriasis patients, its crucial to balance these risks with the potential benefits