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The use of GSH precursors like N-acetyl cysteine, enhancers of nuclear factor erythroid 2-related factor 2 (Nrf2) like sulforaphane, melatonin, and many more molecules involved in antioxidant defense were proposed as supplementation of other idiopathic pulmonary fibrosis therapies (130)

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Mechanism of Action Angiogenic Modulation and Growth Factor Upregulation The mechanism of BPC-157 is centered on its ability to trigger the Early Growth Response 1 (EGR-1) gene and subsequently upregulate the Vascular Endothelial Growth Factor (VEGF)

The results clearly indicated that the five glutathione mutants had shorter roots on control plates than the WT already after 4 days (Supplementary Figure S2)

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