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2 nd ed: Thomson Reuters

It communicates with your brain to reduce appetite, tells your liver to slow glucose production, and slows gastric emptying so you feel full longer

Following administration in preclinical models: Intravenous administration provides immediate systemic availability Intramuscular injection demonstrates absorption with peak levels within 1-2 hours Individual peptide components show variable tissue distribution patterns Blood-brain barrier penetration demonstrated for certain neuropeptide fractions Distribution studies indicate that some peptide components can cross the blood-brain barrier, though the extent varies by molecular weight and specific peptide characteristics

To investigate this issue Mojsov, Drucker and Habener joined forces with Jacques Philippe and William Chick, two other researchers at MGH

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