Langer J, Aberasturi DJD, Aizpurua J, Alvarez-Puebla RA, Liz-Marzn LM
For immunoblot, samples were separated by SDSPAGE
HUVECs were treated with 1.0 g/ml BPC 157 and the protein expressions of Src, Cav-1, eNOS and their phosphorylated forms were analyzed by western blot
& Young, R
Importantly, GHK-Cu did not negatively impact cell proliferation or NO secretion in these macrophages, suggesting its protective effects were specific to inflammatory pathways rather than general cytotoxicity [1]
Oxidative stress is a stress state that causes an imbalance between oxidative and antioxidative effects in the body, leading to inflammatory infiltration of neutrophils, increased protease secretion and the production of numerous oxidative intermediates, causing oxidative damage and interfering with the metabolic activities of normal organs (18,20,21)