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This is likely due to the fact that MT-1 has a much shorter half-life than MT-2 at around 1 hour and its effects are much more short-lived

doi: American Diabetes Association Professional Practice Committee

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Dose-dependent effects of L-carnitine supplementation on lipid profiles and glucose levels: Systematic review and meta-analysis of 21 RCTs

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PPAR is able to upregulate the expression of almost all genes involved in the carnitine shuttle mechanism (e.g., CPT1, CPT2, CACT and CrAT) [193, 194]