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10.1038/s41586-019-1705-2 14 BiamonteF.SantamariaG.SaccoA.PerroneF

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These lines are frequently called "large bores" or "trauma lines"

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Frost et al

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In addition, zinc plays a vital role in the thyroid hormones metabolism by regulating thyrotropin-releasing hormone (TRH) and TSH synthesis and modulating the structures of essential transcription factors involved in synthesizing thyroid hormones (177, 178)

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