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The efficacy of systemic GLP-1R agonists to attenuate cocaine seeking is associated with increased activity of GABA neurons in the VTA While an emerging literature indicates that activation of VTA GLP-1Rs is sufficient to reduce drug-seeking behavior 8,14 , the cell type-specific neural mechanisms underlying the efficacy of GLP-1R agonists and increased GLP-1 signaling in the VTA on cocaine seeking remain largely unknown
Biol Chem 390, 191214.CrossRefGoogle ScholarPubMed Weschawalit, S, Thongthip, S, Phutrakool, P, et al
If you are taking both semaglutide and an SGLT-2 inhibitor, which some diabetes management protocols include, the UTI risk from the SGLT-2 component deserves attention
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