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To explore the mechanisms underlying PGC developmental failure, we carried out single-cell RNA sequencing (scRNA-seq) of wild-type and Trim37 -deficient PGCs and SCs at E8.5 and E9.5 (Fig

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Berberine Attenuates Cognitive Impairment and Ameliorates Tau Hyperphosphorylation by Limiting the Self-Perpetuating Pathogenic Cycle between NF-b Signaling, Oxidative Stress and Neuroinflammation

Then, cells were washed with PBS three times

Moreover, IGF-1 nasal spray provides a targeted distribution within the nasal passages, allowing peptides to act either systemically or locally

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