Proposed Mechanisms Preventing GABA receptor downregulation Counteracting compensatory NMDA glutamate receptor sensitization Stabilizing benzodiazepine receptor configuration (preventing shift to inverse agonist state) Upregulating GABAergic neurotransmission through pathways distinct from benzodiazepine action itself This tolerance prevention has profound clinical implications
This could further reduce your appetite, and improve your mood, eating habits, energy, motivation, and physical training, supporting your wellness and weight loss goals
However, these side effects are also more common at the beginning of treatment and may decrease as the body adjusts to the medication
& Olefsky, J
In addition, there is evidence that GLP-1 has effects on adipose tissue and skeletal muscle that are extra-pancreatic 23,24
Nauck MA, Muus Ghorbani ML, Kreiner E, Saevereid HA, Buse JB, Investigators LPCobotLT