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Journal of pharmacological sciences , 108 (1), 7-17
A phase 3 trial called REDEFINE-1 included over 3,400 people who were overweight or obese with one or more comorbidities (like hypertension or cardiovascular disease), but not type 2 diabetes
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Their integration into therapeutic regimens may offer advantages over conventional approaches, particularly in promoting mucosal healing and maintaining gut barrier integrity
These uses are investigational and not established as approved medical indications
Heat is used to eliminate microbes and other contaminants from final product
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