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Our comments as a key stakeholder were taken on board and many improvements were made before publication

According to the public registry, the trial was completed, and the results suggest a favorable safety profile with no significant adverse events reported (ClinicalTrials.gov Identifier: NCT03416053)

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[6] The most defensible description is that AOD9604 was associated with beta-3-adrenergic-receptor-related adaptations in mouse adipose tissue, while the direct molecular target responsible for the reported metabolic effects remained unresolved