semaglutide mash pdufa The FDA has approved Wegovy (semaglutide) as a treatment for metabolic-associated steatohepatitis (MASH) with moderate-to-advanced scarring, a serious liver condition affecting approximately 6% of US adults. Key highlights of drug development program MASH therapy enters a more

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Younger patients with lower surgical risk and stable weight may require less interruption

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Testing may be appropriate if: Weight loss exceeds 1520% Fatigue, hair thinning or neuropathy develops Persistent vomiting or diarrhoea occurs Dietary intake becomes severely restricted You are in a higher-risk group (e.g., premenopausal women, older adults, GLP-1 + metformin users) Monitoring should be personalised rather than automatic