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This may explain why side effects are relatively rare compared to pharmaceutical approaches that introduce foreign signaling molecules

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This is qualitatively different from what anti-inflammatory medications produce, because the tissue itself is changing rather than just the symptom signal being blocked

The consistency of the safety profile across short-term and long-term trials suggests that AOD-9604 does not produce cumulative toxicity or delayed adverse effects that emerge only with chronic administration

14 When GSH is depleted or oxidized, bacteria become hypersensitive to oxidative and nitrosative stress

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