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16 Joint & Musculoskeletal Pain Overweight and obesity have a profound impact on overall physical function, musculoskeletal pain and both the development and progression of osteoarthritis

Contraindications: pregnancy and breastfeeding (no reproductive data), active cancer or cancer history (angiogenesis could theoretically feed tumor growth), children under 18 (no pediatric data)

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References 1) Ra, Song-Gyu, et al