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"Randomized double-blind placebo-controlled trial of acetyl-L-carnitine for the prevention of taxane-induced neuropathy in women undergoing adjuvant breast cancer therapy." J Clin Oncol 31(20): 2627-2633

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One hypothesis that is sometimes brought up is that APAP-induced cell death might be caused by apoptosis, which rapidly deteriorates into secondary necrosis [11]