It is usually mild, manageable, and improves with time
When initiating Ozempic, consider arranging an extra INR check after starting treatment, after dose changes, and following significant gastrointestinal illness
Common effects may include nausea, diarrhea, constipation, dry mouth, sweating, tiredness, dizziness, sleep changes, and sexual side effects
[1] [2] Important safety considerations include a boxed warning for risk of thyroid C-cell tumors (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2)
Additionally, increased plasma insulin, decreased triglycerides, and improved myocardial glucose uptake were observed in the GLP-1 treated group [74]
One possible way to stop the weight from coming back is to transition to other medications or scale back the dose rather than stop treatment altogether