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APP/PS1 transgenic mice show depressive-like behaviors, demonstrated by reduced sucrose preference, increased immobility in the TST and forced swimming test (FST), as well as social withdrawal before A plagues are detected (Gao et al., 2018

It is a growth hormone-releasing peptide, meaning it is discussed for its ability to stimulate growth hormone secretion

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SLC25A40 knockdown caused a reduction in the release of IL-1 in LPS-primed and nigericin-stimulated BMDMs (Fig