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Novel therapies targeting mitochondrial quality control pathways, such as mitophagy enhancers and antioxidant regulators, may represent a new class of interventions capable of modulating OA pathophysiology at the cellular level (Picca et al., 2020
Supports healthy detoxification processes
This experiment is part of the cooperation project MitoCow funded by the German Research Foundation (DFG, 202989534)
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The effect of acylcarnitine on insulin sensitivity is also related to the saturation of acylcarnitine, with myotubes incubated with C16-carnitine exhibiting reduced insulin sensitization, whereas the accumulation of oleoylcarnitine (C18:1-carnitine) and linoleoylcarnitine (C18:2-carnitine) increases insulin sensitization [77]
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