tirzepatide + pyridoxine hcl and for weight loss and reduced side effects 🤔 confused : r/tirzepatidecompound

doi: 10.1021/jacsau.2c00130 de Bray A, Roberts AG, Armour S, Tong J, Huhn C, Gatin-Fraudet B, Romann K, Shilleh AH, Jiang W, Figueredo Burgos NS, Trott JPP, Viloria K, Nasteska D, Pearce A, Miyazaki S, Tomlinson JW, Owen DM, Nieves DJ, Ast J, Cyranka M, Epanchintsev A, mml C, Reimann F, Soykan T, Ladds G, Adriaenssens AE, Trapp S, Jones B, Broichhagen J, Hodson DJ

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Holsts laboratory played a central role in characterizing the active intestinal form of GLP-1, demonstrating its therapeutic potential in diabetes, as well as obesity treatment, and developing early drug analogs

GLP-1 therapies are not recommended in people with a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia type 2 (MEN2)