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Clinical trial data from the STEP program documented hair-related adverse events, though at rates not dramatically different from placebo when controlled for weight loss magnitude

30 Concentrations used in the study (25-100 mM) were even lower than those found in commercial tanning lotions (330 mM)

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They also highlight the need for future clinical trials to more conclusively determine the dose and duration of GLP-1 receptor agonist-based treatments in patients addicted to different types of substances, including amphetamines, opioids, and benzodiazepines

Complementary mechanisms