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Progenitor cells are integrated directly in the damaged barrier, particularly in the endothelium and the surrounding tissue, and release mediators that contribute to barrier repair after stroke (213), but a recent phase I/II clinical trial has evaluated the administration of intravenous allogenic MSC in chronic stroke, suggesting behavioral gains and laying the ground for a randomized controlled trial (214)
Journal of natural science, biology, and medicine
12 BergaminiE.CavalliniG.DonatiA.GoriZ
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