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The significant increase in taurine, xanthine, and glutathione in tamoxifen-resistant cells indicates an increase in antioxidative activity in the cells, especially in the cell line under continuous tamoxifen treatment

Mechanistically, GHRP-6 sustained cellular antioxidant defense, upregulated the prosurvival gene Bcl-2, and preserved cardiomyocyte mitochondrial integrity

It involves turning on genes that produce the two enzymes responsible for making GSH

Both TB-500 and BPC-157 may also support angiogenesis

A 2022 SS-31 as a mitochondrial protectant in the treatment of tendinopathy: evaluation in a murine supraspinatus tendinopathy model

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