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There was no difference in rate of hypoglycemia between DPP-4 inhibition and placebo in four of the studies (9093) whereas one study showed an increased rate of hypoglycemia with the combination (81)
Furthermore, they contribute to weight loss and serve as an alternative to insulin, representing a non-insulin approach to diabetes management
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In clinical trial data, nausea, diarrhoea, constipation and vomiting are consistently among the most common side effects
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