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Consistent with these findings, GSH-depleted mice showed significantly decreased weights of liver and epididymal (visceral) white adipose tissue (eWAT) (Figure 2, D and E), while weights of inguinal (subcutaneous) white adipose tissue (iWAT), brown adipose tissue (BAT), or skeletal muscle remained unchanged (Supplemental Figure 2, FH)

It also showed increased levels of type I collagen and glycosaminoglycans

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53 In preclinical models of NAFLD, NAC has been shown to block fat accumulation in the liver