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Many factors including mitochondrial and endothelial dysfunction, hyperglycemia, dyslipidemia, unhealthy diet might generate oxidative stress in individuals with obesity, leading to direct effects on adipocytes maturation and differentiation as well as on hypothalamic center of satiety and huger behaviour [115, 116]

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Redox Biol | DOI: 10.1016/j.redox.2022.102595 Yang, Y

Expression of mutant SOD1 in neurones did not result in ALS symptoms