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Other factors that trigger pyocyanin-mediated oxidative stress in airway epithelial cells include inhibition of catalase activity and depletion of NADPH ( Oxidative stress mediated by pyocyanin has a strong inhibitory effect on A549 cell multiplication (growth) and confluence
Acknowledgements Work in T.P.s laboratory was supported by NIH grants (R37CA222504, R01CA227649, R01CA283049, R01CA262562 and R01CA297605) and an American Cancer Society Research Scholar Grant (RSG-17-200-01TBE)
cerevisiae In yeast, glutamate can be synthesized through the activation of the GDH pathway when ammonium is present in abundant levels
When any antioxidant, including glutathione, retains all its electrons (making the number of protons and electrons in the molecule equal), it is in a reduced state
Goodwin GM, Aaronson ST, Alvarez O, Atli M, Bennett JC, Croal M, et al
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