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Although the DLM reduced glutathione was unchanged between peak disease and recovery, indicating that resolving oxidative stress is important during EAE, metabolites protective against oxidative stress (nicotinamide and nicotinic acid) 26 and decreased at peak disease were elevated to homeostatic healthy levels at recovery (Fig

Disulfide Bond Integrity Verification (Cys7-Cys14) Because the Cys7-Cys14 intramolecular disulfide bond is required for the lipolytic conformation, every lot is checked for disulfide bond integrity using non-reducing LC-MS or Ellman's reagent analysis