If they are also used in other thiol ATs, this can potentially lead to removing their limitations (at least some of them) and enhancing their therapeutic potential
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As the primary factors for the reduced anticancer effect 1) the reduced delivery and uptake of the anticancer agent, 2) the need for the conversion of molecular oxygen (O 2 ) into reactive oxygen species (ROS), 3) the preferred therapeutic effect against highly proliferating cells, which is reduced under hypoxic conditions, or 4) adaptation of the cancer cells by promoting cell survival and upregulating certain resistance pathways, has been suggested 1,2,3,4,5
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They are claimed to treat or prevent conditions ranging from infant colic to cardiovascular disease, respiratory infections, and certain cancers
doi: 10.1155/2014/690704 74 RudnickaESuchtaKGrymowiczMCalik-KsepkaASmolarczykKDuszewskaAMet al