REDEFINE 2: Efficacy in Type 2 Diabetes REDEFINE 2, announced in March 2025, addressed a distinct population: 1,206 adults with obesity or overweight and type 2 diabetes across 12 countries, randomised in a 3:1 ratio to CagriSema or placebo for 68 weeks
Step 2: Preparing for Your First Dose While GLP-1 medications are generally well-tolerated, a little preparation can go a long way to ensure the best experience, especially in the first few weeks as your body adjusts: Hydrate Well: Drink plenty of water throughout the day
Acetaminophen is often a safer alternative
They also noted that patients who experienced moderate to severe gastrointestinal adverse events, like gastroparesis, were also more likely to discontinue GLP-1 use
Roznere, I., Watters, G
Duration of Treatment Wegovy is designed for long-term, chronic management