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It is studied in preclinical and laboratory models for its ability to activate target pathways and modulate downstream molecular signaling associated with endocrine regulation
Thiazolidinediones: the forgotten diabetes medications
Thyroid Conditions During Pregnancy
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Rodents have faster metabolic rates, different CYP450 expression patterns, and potentially different blood-brain barrier penetration
The authors noted that discontinuation rates may have limited the overall effectiveness of therapy, particularly given that many patients did not reach target doses typically prescribed for weight loss
