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Semaglutide , originally developed to treat type 2 diabetes, has gained widespread attention for its efficacy in promoting weight loss

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"Fortunately, these medications, to date, have proven to be comparatively low risk," said Dr

Tirzepatide, marketed as Mounjaro, is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist licensed in the UK for type 2 diabetes mellitus and chronic weight management

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In contrast, the outer mitochondrial membrane (OMM), which delimits the IMS and the cytosol, has a relatively smooth and homogenous structure, and is permeable to most ions and small uncharged molecules ( Figure 1 Consistent with its customary epithet as the powerhouse of the cell, mitochondria play a pivotal role in cellular bioenergetics, through the production of ATP via oxidative phosphorylation (OXPHOS) ( 2 and NADH ( 2 ), these complexes transport protons against a concentration gradient from the matrix to the IMS