It is contraindicated in patients with uncontrolled hypertension, seizure disorder, current or prior anorexia/bulimia, and those taking monoamine oxidase inhibitors
For example, pseudogout , caused by a different type of crystal (calcium pyrophosphate), causes the same type of hot, red joint, and the same rapid acceleration of pain as does gout
Amylin regulates gastric emptying, suppresses glucagon secretion, and promotes satiety via central nervous system pathways
Receptor biology, in other words, predicts both the benefit and the burden of these drugs in the brain
GLP-1 receptor agonists work by mimicking the naturally occurring incretin hormone GLP-1, which enhances glucose-dependent insulin secretion, suppresses glucagon release, and slows gastric emptying
Refrigeration optional