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Interestingly, CBS is upregulated by transcription factors such as nuclear factor erythroid 2-related factor 2 (NRF2) 17 , SP1/3 18 , and NFY 18 and its upregulation confers resistance against ferroptosis in ovarian cancer cells 17
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The UK Biobank has already received the ethical approval from North West Multi-centre Research Ethics Committee (MREC) which covers the UK
Moreover, because carnitine also offers antioxidant and anti-inflammatory effects, it has been shown to reduce markers of vascular injury in patients undergoing hemodialysis and in those with peripheral vascular disease (11, 12)
Completely agree with the shift toward systems level thinking
A novel group of glutaredoxins in the cis-Golgi critical for oxidative stress resistance
