how and where to inject tirzepatide You should rotate your injection

Step 4: Swirl Gently Never Shake Remove the syringe

Common Side Effects & Considerations Common side effects are similar to semaglutide and include nausea, vomiting, diarrhea and constipation

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Semaglutide mimics glucagon-like peptide-1 (GLP-1), a hormone that slows stomach emptying, increases feelings of fullness, and reduces hunger signals in the brain

These numbers represent averages across large trial populations

Increased urination during the first few weeks often indicates glycogen depletion and fluid redistribution, which are signs that your body is responding to reduced caloric intake and beginning to burn stored energy