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Kwashiorkor and marasmus represent clinical forms of protein-energy malnutrition (PEM) [108]

Unlike semaglutide, tirzepatide, and retatrutide (which are all peptide-based), orforglipron is a synthetic small molecule that binds to and activates the GLP-1 receptor

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Some studies suggest that it may be more effective than Semaglutide, particularly in weight reduction

The medication also slows gastric emptying, meaning food stays in the stomach longer and nutrient absorption is more gradual