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Here we report cryo-electron microscopy (cryo-EM) structures of human OCTN2 in a substrate-free inward-facing conformation, a substrate-bound occluded conformation, and an ipratropium-bound inward-facing conformation, revealing how OCTN2 binds and transports carnitine

SUSTAIN-7 (N=1,201) compared semaglutide 0.5 mg and 1.0 mg against dulaglutide 0.75 mg and 1.5 mg over 40 weeks

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