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A less efficient reaction is possible for longer acyl groups with fatty acid chains of up to ten carbon atoms in length [144]
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However, the potential for delaying or preventing the progression of T2DM in patients treated with GIP and GLP-1 remains uncertain, as there is currently no definitive evidence from human studies demonstrating that enhanced incretin activity directly affects -cell mass or alters the progressive loss of insulin secretory capacity in humans
Thermal stability was measured following solubilization in n -dodecyl--d-maltopyranoside supplemented with cholesteryl hemisuccinate (see Methods)
Funding No funding was provided for this study
Robustness A slight modification in the methanol ratio ( 1%), a refined adjustment in the distance travelled by the solvent ( 0.5 cm), and in the time of saturation ( 5 min) were elegantly employed to evaluate the robustness of the HPTLC method
