Clinical Decision Pathway: Nutritional Oversight During GLP-1 Therapy Step 1: Is There Evidence of Malabsorption
When to seek medical attention: Contact your GP promptly if you experience recurrent episodes of right upper abdominal pain Seek urgent medical assessment (A&E or call 999) if you develop severe persistent pain, high fever, jaundice, or signs of sepsis If you develop severe, persistent abdominal pain that radiates to your back, especially with vomiting, seek urgent medical care as this could indicate pancreatitis
Clinical studies of tirzepatide show that gastrointestinal side effects occur in up to 40% of patients, with nausea being more common than heartburn specifically
Nature (1996) 379(6560):6972
Fatigue and Energy Some users report mild fatigue, particularly during the first few weeks of use or after dose increases
8 (graphic generated by ADW using creative commons- and Adobe-licensed images and PowerPoint)