[11] Long-term metformin therapy reduces calcium-dependent intrinsic-factor binding, lowering B12 absorption and potentially necessitating higher or more frequent parenteral doses
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These drugs are typically recommended for people who: Have a BMI of 30+ , OR Have a BMI of 27+ with a weight-related health condition , such as type 2 diabetes, high blood pressure, insulin resistance, or sleep apnea
High quality Supplements arent regulated by the FDA in the same way as other drugs, so you should always do a little extra research before choosing a supplement brand
[1] While some fatty acids can, long chain fatty acids cannot pass through the mitochondrial membrane