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High doses may cause temporary headaches due to increased NAD+ turnover and mitochondrial activity

These hypotheses will need to be explored in a randomized study

While individual components like choline have established roles in hepatic lipid metabolism, controlled trials demonstrating clinically meaningful weight loss from MIC-B12 injections are lacking

injection of non-pharmaceutical-grade compounds carries infection and inflammatory risks

In that case, a doctor will likely recommend B12 shots to get their levels up to where they should be

However, potential concerns: High doses of B12: While very rare, taking extremely high doses of B12 could theoretically lead to side effects, including potential issues with blood clotting