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Baseline values for several biomarkers were significantly different between the BH4 and placebo groups
Too much urea, a waste product in the blood, can harm various tissues, especially the nervous system
According to the FDA prescribing information, these gastrointestinal symptoms are dose-dependent and represent the primary reason for treatment discontinuation in clinical trials
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Patients who lost the most weight regained the most in absolute terms
The term has, however, greatly evolved beyond this simple and easy-to-digest scientific definition
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