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Nevertheless, significant shortcomings existed in such studies, including relatively short mean follow-up times (of less than 2 years in the RCTs), selected patient cohorts, and limited sample sizes

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Angew Chem Int Ed Engl 53(47):1279412798 Wang X et al (2013) Au-nanoparticle coated mesoporous silica nanocapsule-based multifunctional platform for ultrasound mediated imaging, cytoclasis and tumor ablation

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