The role of HOTYR as a chemo-preventive anti-carcinogenic compound has received attention in human carcinoma cells in many in vitro studies showing significant effects in several cancer cell lines as main responsible compound, either alone or in a synergistic manner (82), arresting the cell cycle at any of its phases, producing differentiation, apoptosis, or preventing DNA from oxidative stress (Table 2)
7, 12 June 2013, Okobi, Okelue E., et al
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