stopping and restarting glp-1 Why are patients meds? Restarting a GLP-1 After Stopping:

318,319 Expression of mutant DMD gene results in progressive muscle degeneration leading to various problems with locomotion, ambulation, as well as deficits of cardio-vascular and respiratory systems

Sharma and Dietz, 2006)

PubMed Goldstein, A.L., Hannappel, E., Sosne, G., & Kleinman, H.K

ongoing monitoring is still needed Bariatric surgery may be considered for severe obesity Medications First-line medication Reduces CSF production Start low, increase gradually Side effects: tingling, carbonated drinks taste flat, kidney stones Alternative or addition to acetazolamide May help with headache Can cause weight loss (advantage in IIH) Side effects: cognitive slowing, tingling Furosemide Sometimes added to acetazolamide Monitor potassium GLP-1 Receptor Agonists (Emerging Treatment) GLP-1 medications (such as semaglutide, sold as Ozempic or Wegovy) are showing significant promise for IIH

The following characteristics define WBCILs formulation quality for bulk API manufacturing

Abdul-Ghani M, DeFronzo R