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Encouraged by their success with the dual agonist, Tschp and DiMarchi wondered if it was possible to go a step further and develop a peptide to simultaneously target three key metabolically-related hormone receptors: GLP-1, GIP and glucagon
An IV infusion ensures these compounds are available at therapeutic levels without relying on the digestive system for absorption
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they are solely presented to complement the intake of nutrients in a normal diet
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Although the comparison between 34 hr and 58 hr showed no differences in most metabolites except butyrates and OA, we also noticed that some metabolites peaked in 34 hr, while other metabolite kept increasing until 58 hr (cis-aconitate, succinate, nicotinamide (Fig
