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In addition, multi-acting unimolecular peptides have emerged as highly promising therapeutics in obesity and T2D, typified by the GIP/GLP-1 hybrid peptide tirzepatide
Conversely, the general hormonal turbulence could, theoretically, affect the very early stages of pregnancy and implantation, though this is highly speculative and not proven
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This impairment compromises mitochondrial ATP production, resulting in cellular energy deficits (Siddiqui et al., 2016)
Nat Med (2003) 9:3525
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