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The most frequently reported side effects of Saxenda are gastrointestinal in nature and include: Nausea (affecting approximately 40% of patients, particularly during dose escalation) [1] [2] Diarrhoea (reported in around 20% of users) Constipation (affecting approximately 20% of patients) Dyspepsia and abdominal pain Gastro-oesophageal reflux disease (GORD) Other recognised adverse effects include injection site reactions, headache, dizziness, fatigue, and hypoglycaemia (particularly in patients with type 2 diabetes taking concomitant glucose-lowering medications, especially sulfonylureas or insulin)

Semaglutide dosing for weight loss follows a structured escalation called titration

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